When the color has drained out of things.

For the woman who keeps going, and has stopped feeling much of anything about it.

Nothing is wrong, exactly. That's what makes it so hard to explain.

She gets up. She does the things. She can laugh at dinner. But somewhere along the way the color drained out of it, and she can't say when. The things that used to light her up feel like tasks now. She's tired of hearing herself say "I'm fine."

Depression doesn't always look like falling apart. Sometimes it looks like a woman who keeps going.

When you've tried what you were told to try

Maybe you've done therapy. Maybe you've tried medication, or a few. Some of it helped. Some of it took the edges off without giving you back to yourself. You're not looking for a miracle. You're looking for something that reaches a little further.

What ketamine is, and what it isn't

Ketamine has been used in medicine for decades. In 2019 the FDA approved a related form, esketamine (Spravato), for treatment-resistant depression, given only in certified clinics. The ketamine prescribed for at-home use is different. Prescribing it for depression is off-label: legal and common when a licensed physician does it, but not FDA-approved for that purpose.

Research on ketamine for depression is promising and still growing. It doesn't work for everyone, effects can fade, and anyone who promises you an outcome isn't being straight with you. For the full background, read Ketamine for Women: The Complete Guide and Is Ketamine Legal in Colorado?

That's the idea behind RESET: the ceremony can open something, and what helps it last is what you practice in the weeks after. (Why Insight Isn't Enough explains why.)

Is it safe for me?

A licensed physician decides that, not me. Before you join, they review your medical and mental health history, your medications and your blood pressure, decide whether ketamine is safe for you, and write the prescription if it is. Some histories call for extra care, and some mean ketamine isn't the right fit. You'll be told plainly either way.

On ceremony day a facilitator is with the group from beginning to end, and we have your address and an emergency contact before every ceremony. Read Is Ketamine Therapy Safe? and Is At-Home Ketamine Safe? for the details.

If you are in crisis right now, RESET is not the right first step. Please call or text 988 (Suicide & Crisis Lifeline), or call 911.

What RESET looks like alongside depression

• You're not doing it alone. A circle of women and an experienced facilitator, together for the whole ceremony.
• A month with a shape. A ceremony, then live integration gatherings. Something steady to come back to.
• Your other care stays in place. RESET isn't a replacement for therapy or psychiatric care, and you don't have to give either up to join.
• No rush. RESET is ongoing. There's no wrong month to begin, and about a year is where real change tends to land.

Ketamine is a prescription medicine. Using it for mental and emotional health is off-label, which is legal and common when a licensed physician prescribes it, but it means the FDA has not approved it for that purpose. Esketamine (Spravato) is the only FDA-approved form for depression, and it is given in certified clinics.

Questions women ask

Can ketamine help with depression?

Research on ketamine for depression is promising, and esketamine (Spravato) is FDA-approved for treatment-resistant depression. At-home ketamine for depression is off-label, it doesn't work for everyone, and results can fade. A licensed physician decides whether it's safe and appropriate for you.

Does this replace my antidepressant or my therapist?

No. Never stop or change a medication without talking to your prescriber. The physician reviews everything you take, and many women keep working with their therapist alongside RESET.

What if I'm in crisis?

Please don't wait for RESET. Call or text 988 (Suicide & Crisis Lifeline) or call 911. RESET is not crisis care.

Do I need a diagnosis to join RESET?

No. A licensed physician evaluates you for medical safety and decides whether to prescribe.